When performing an allotransplantation, donor cells, are transferred to a recipients. When successful, the engraftment is maintained, although the recipient may have its own cells present as well as cells from the donor.

This chimeric state of the transplant is dynamic and a relapse to a diseased state in which recipient cells increasingly return should be avoided. Monitoring the post-transplant chimeric status is important as it could indicate an imminent relapse.

Earlier relapse detection with qPCR

KMRtype® & KMRtrack® Chimerism Monitoring Reagents

– Reduced lab workflow
– Simultaneous typing of 8 Samples
– Multiple donor analysis
– Compatible with multiple real time thermo cyclers

KMRengine® Chimerism Analysis Software

– Automated data analysis
– Longitudinal data storage and reporting
– Protocol generation and flexible experiment setup
– Enables direct importing into LIMS

HLA-KMR™ HLA loss detection assay's

– Most frequent allele groups of HLA-A, C and DPB1
– Applicable with KMRtrack protocol
– Fully integrated with KMRengine