In an effort to overcome the sensitivity and analysis shortcomings of STR-based transplant monitoring methods, and to improve upon the current state of the art in qPCR-based chimerism analysis and laboratory workflow, GenDx has created a new assay and software suite.

Our workflow utilizes a panel of 39 multiplexed qPCR research assays and KMRengine software to comparatively genotype multiple samples on a single plate. The KMRtype Core kit consists of 10 mixtures of 3 qPCR assays each and the KMRtype Extended kit consists of another 3 mixtures of 3 qPCR assays each.

Multiple Donor Analysis

For recipients receiving serial transplants, monitoring used to be challenging. With our highly sensitive system multiple donors can be traced simultaneously. With the increased use of double cord-blood donations this feature improves the opportunities for highly sensitive and longitudinal monitoring